

Vayne Synergies Patch 15.10: Best and Worst Picks with Vayne
Find the best champions to pair with Vayne for Bottom Lane using win rate data on LoLTheory. Optimize your team composition in LoL Season 15 Patch 15.10.
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Classic
Based on the typical player's experience with each champion—e.g., the average Vayne player has more games with Vayne than the average Ahri player has with Ahri
Fixed Experience
∙ Expand champion poolAssume a standard experience of 25 games per champion for fair comparison. Use this to understand the meta and expand your champion pool
Personalized
∙ Win more short termMaximize your next game's win rate by analyzing your ranked history—performance and game count—for all champions over the last 10 patches.
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Best Picks with Vayne
Champions that perform well alongside Vayne in team compositions. Listed by highest win rates when paired with Vayne in Platinum ranked matches.
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Worst Picks with Vayne
Champions that underperform when paired with Vayne. Ranked by lowest win rates when on the same team in Platinum matches.
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Be aware that Vayne becomes significantly stronger after 25 minutes. Position to protect her in late-game teamfights, as her Silver Bolts (W) and invisibility from Final Hour (R) make her your primary damage dealer.
Basic Late Game Team Fight
In teamfights, position yourself to absorb attention and crowd control when Vayne activates Final Hour (R). This creates space for her to maximize her damage output with Tumble (Q) and invisibility.
Team Fight Late Game
Fight near walls and tight corridors when grouping with Vayne. These areas maximize her Condemn (E) potential to stun enemies against terrain, creating prime follow-up opportunities.
Skirmish Team Fight
When supporting Vayne, place Control Wards in river and tribush during the laning phase. This protects her vulnerable early phase and allows her to farm safely toward her power spikes.
Lane Phase
Position yourself between Vayne and enemy divers or assassins when playing tanks. Despite her Silver Bolts (W) being effective against high-health targets, she's extremely vulnerable to burst damage.
Team Fight
Stay near Vayne during the mid-game (15-25 minutes) when rotating or farming side lanes. Her short attack range makes her vulnerable to ambushes when alone, despite her mobility from Tumble (Q).
Basic Skirmish
Wait for Vayne to apply Condemn (E) before using your crowd control abilities. Coordinating your CC chain after her stun leads to longer lockdown duration and more effective takedowns.
Skirmish Team Fight
Allow Vayne to focus on a single target in teamfights when possible. Her Silver Bolts (W) stacks reset when switching targets, so letting her apply all three stacks maximizes her true damage.
Team Fight