Vayne Splash Art
Vayne

Vayne Synergies Patch 16.15: Best and Worst Picks with Vayne

Find the best champions to pair with Vayne for Bottom Lane using win rate data on LoLTheory. Optimize your team composition in LoL Season 16 Patch 16.15.

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Based on the typical player's experience with each champion—e.g., the average Vayne player has more games with Vayne than the average Ahri player has with Ahri

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Assume a standard experience of 25 games per champion for fair comparison. Use this to understand the meta and expand your champion pool

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Maximize your next game's win rate by analyzing your ranked history—performance and game count—for all champions over the last 10 patches.

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Best Picks with Vayne

Champions that perform well alongside Vayne in team compositions. Listed by highest win rates when paired with Vayne in Platinum ranked matches.
ChampionRoleWR%
SingedSinged1.58% PR 55.02% FiddlesticksFiddlesticks1.14% PR 55.00% MilioMilio4.32% PR 54.16% ZacZac1.71% PR 53.80% XerathXerath2.49% PR 53.76% Nunu & WillumpNunu & Willump1.11% PR 53.24% LilliaLillia1.52% PR 53.09% HeimerdingerHeimerdinger0.76% PR 52.94% BraumBraum2.20% PR 52.78% GangplankGangplank2.96% PR 52.66% ShenShen2.28% PR 52.59% VeigarVeigar1.83% PR 52.58% LuxLux2.27% PR 52.52% TeemoTeemo1.92% PR 52.49% NocturneNocturne3.33% PR 52.48% RammusRammus0.63% PR 52.41% VladimirVladimir2.87% PR 52.36% SorakaSoraka3.44% PR 52.34% JannaJanna3.35% PR 52.31% HweiHwei2.24% PR 52.22% MalphiteMalphite3.13% PR 52.21% ZileanZilean1.75% PR 52.14% KayleKayle1.40% PR 52.13% AkaliAkali1.33% PR 52.12% EkkoEkko2.04% PR 52.11% Vel'KozVel'Koz0.65% PR 52.01% LissandraLissandra2.42% PR 52.00% VladimirVladimir0.81% PR 51.97% LuluLulu11.10% PR 51.94% TalonTalon2.70% PR 51.93% EvelynnEvelynn1.23% PR 51.88% VexVex1.44% PR 51.84% HecarimHecarim2.64% PR 51.84% IvernIvern0.47% PR 51.76% AhriAhri5.21% PR 51.68% UdyrUdyr1.07% PR 51.66% EliseElise0.98% PR 51.61% ShacoShaco2.63% PR 51.53% Cho'GathCho'Gath1.22% PR 51.52% NamiNami5.01% PR 51.50% TaricTaric0.68% PR 51.49% KarthusKarthus0.70% PR 51.45% RakanRakan1.49% PR 51.37% SonaSona2.35% PR 51.33% ZaahenZaahen1.73% PR 51.32% KatarinaKatarina4.29% PR 51.31% PoppyPoppy0.79% PR 51.30% RellRell1.59% PR 51.27% ShyvanaShyvana2.06% PR 51.26% PantheonPantheon1.29% PR 51.22% ViktorViktor4.78% PR 51.20% Aurelion SolAurelion Sol0.71% PR 51.17% SejuaniSejuani0.96% PR 51.16% KaynKayn3.25% PR 51.15% OrnnOrnn1.87% PR 51.15% NidaleeNidalee1.24% PR 51.14% TaliyahTaliyah0.87% PR 51.06% KassadinKassadin2.07% PR 51.02% FizzFizz2.42% PR 50.98% AuroraAurora1.20% PR 50.96% BriarBriar2.40% PR 50.95% EkkoEkko1.94% PR 50.94% DianaDiana2.08% PR 50.86% LeonaLeona2.72% PR 50.86% GragasGragas1.28% PR 50.77% TryndamereTryndamere1.69% PR 50.77% MordekaiserMordekaiser4.41% PR 50.69% DianaDiana1.68% PR 50.69% KledKled0.85% PR 50.67% Twisted FateTwisted Fate2.40% PR 50.66% EliseElise0.34% PR 50.63% SyndraSyndra4.64% PR 50.62% WukongWukong2.71% PR 50.56% ViVi2.63% PR 50.54% ZoeZoe1.44% PR 50.52% AniviaAnivia1.27% PR 50.52% MalzaharMalzahar3.01% PR 50.45% SettSett2.74% PR 50.42% ThreshThresh6.69% PR 50.42% Jarvan IVJarvan IV3.42% PR 50.40% JaxJax0.79% PR 50.39% AnnieAnnie0.89% PR 50.36% FioraFiora2.25% PR 50.33% IllaoiIllaoi1.08% PR 50.27% KennenKennen0.96% PR 50.22% SeraphineSeraphine3.17% PR 50.19% AkaliAkali2.83% PR 50.15% AatroxAatrox0.71% PR 50.12% Kha'ZixKha'Zix3.29% PR 50.05% NasusNasus1.49% PR 50.01% GwenGwen1.29% PR 50.01%

Worst Picks with Vayne

Champions that underperform when paired with Vayne. Ranked by lowest win rates when on the same team in Platinum matches.
ChampionRoleWR%
MelMel0.55% PR 43.00% LockeLocke0.88% PR 43.41% YoneYone1.90% PR 44.22% MelMel1.05% PR 46.07% RengarRengar2.73% PR 46.32% Tahm KenchTahm Kench0.91% PR 46.43% PantheonPantheon1.39% PR 46.52% K'SanteK'Sante1.67% PR 46.79% OriannaOrianna1.50% PR 46.84% AzirAzir0.82% PR 46.87% NaafiriNaafiri1.86% PR 47.01% YasuoYasuo3.22% PR 47.10% SwainSwain1.03% PR 47.39% TalonTalon0.60% PR 47.43% JayceJayce0.50% PR 47.54% CamilleCamille3.50% PR 47.57% NautilusNautilus3.49% PR 47.81% QiyanaQiyana1.62% PR 47.90% ViegoViego5.01% PR 47.94% JayceJayce0.33% PR 47.99% ZedZed1.19% PR 48.03% SylasSylas0.65% PR 48.08% VolibearVolibear1.39% PR 48.12% AmbessaAmbessa2.01% PR 48.19% RivenRiven1.53% PR 48.19% NaafiriNaafiri0.69% PR 48.20% YasuoYasuo1.68% PR 48.21% LeBlancLeBlanc2.13% PR 48.23% Master YiMaster Yi2.57% PR 48.30% ShenShen0.94% PR 48.30% JayceJayce2.09% PR 48.31% AkshanAkshan1.28% PR 48.32% BrandBrand0.94% PR 48.36% QiyanaQiyana0.94% PR 48.39% Lee SinLee Sin5.10% PR 48.44% AmbessaAmbessa0.64% PR 48.48% Vel'KozVel'Koz0.96% PR 48.48% XerathXerath0.82% PR 48.62% LockeLocke3.72% PR 48.64% KindredKindred1.04% PR 48.65% BardBard2.66% PR 48.77% SkarnerSkarner0.55% PR 48.80% IreliaIrelia0.94% PR 48.81% PykePyke3.34% PR 48.83% SylasSylas3.76% PR 48.86% RumbleRumble0.77% PR 48.86% AatroxAatrox3.21% PR 48.87% PoppyPoppy1.61% PR 48.92% TrundleTrundle0.83% PR 48.96% CamilleCamille1.34% PR 48.96% NeekoNeeko0.45% PR 48.96% ZedZed3.42% PR 48.99% KarmaKarma3.47% PR 49.07% GalioGalio2.15% PR 49.08% NasusNasus1.48% PR 49.12% CassiopeiaCassiopeia0.89% PR 49.15% BlitzcrankBlitzcrank2.10% PR 49.16% GnarGnar1.87% PR 49.16% ZyraZyra0.75% PR 49.22% GarenGaren3.16% PR 49.29% YoneYone2.91% PR 49.32% OlafOlaf1.31% PR 49.33% RyzeRyze1.45% PR 49.36% SennaSenna2.64% PR 49.36% RenektonRenekton2.53% PR 49.38% GravesGraves5.87% PR 49.40% IreliaIrelia1.93% PR 49.42% GalioGalio0.46% PR 49.53% AmumuAmumu0.89% PR 49.55% SylasSylas4.11% PR 49.55% Tahm KenchTahm Kench0.87% PR 49.57% MaokaiMaokai0.72% PR 49.57% JaxJax3.00% PR 49.58% AlistarAlistar2.22% PR 49.63% LuxLux1.50% PR 49.63% ShacoShaco0.64% PR 49.63% MorganaMorgana1.70% PR 49.63% SylasSylas0.67% PR 49.69% WarwickWarwick0.62% PR 49.70% SionSion1.88% PR 49.74% UrgotUrgot1.44% PR 49.74% YuumiYuumi3.62% PR 49.75% Dr. MundoDr. Mundo2.56% PR 49.77% QuinnQuinn0.65% PR 49.83% YorickYorick1.67% PR 49.91% DariusDarius3.64% PR 49.93% Rek'SaiRek'Sai0.71% PR 49.96% Xin ZhaoXin Zhao1.30% PR 49.96% WarwickWarwick1.33% PR 49.98% Bel'VethBel'Veth2.55% PR 50.01% GwenGwen1.29% PR 50.01%
Learn how to play with Vayne with these essential tips.
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Absorb crowd control and attention for Vayne when she activates R (Final Hour), especially past 25 minutes — this is when her invisibility, bonus movement speed, and Silver Bolts stacks make her the team's primary damage threat.
Team Fight Late Game
Fight near walls and narrow corridors when grouped with Vayne — her E (Condemn) knocks enemies back and stuns them if they collide with terrain, so tight spaces turn it into a reliable follow-up setup.
Skirmish Team Fight
Place control wards in the river and tri-bush during the laning phase — Vayne is weak early and her short range makes farming without dying to a gank difficult without vision.
Basic Lane Phase
Body-block divers and assassins from reaching Vayne when you're playing a frontline champion — her W (Silver Bolts) punishes tanks hard, but she has little defense of her own against burst damage.
Team Fight
Stick near Vayne during the mid-game when rotating or side-farming — her short attack range leaves her vulnerable to ambushes if she's caught alone, even with her Q (Tumble) mobility.
Basic Skirmish
Hold your crowd control until after Vayne lands E (Condemn) — chaining your CC onto her stun extends the lockdown and gives your team a bigger window to finish the takedown.
Skirmish Team Fight
Let Vayne stay on a single target in fights rather than switching — her W (Silver Bolts) stacks reset when she attacks a new enemy, so uninterrupted focus is needed to trigger the true damage proc.
Team Fight